Publications

Carboni, A., Hanson, M.A., Lindsay, S.A., Wasserman, S.A., and Lemaitre, B. (2021) Cecropins contribute to Drosophila host defense against a subset of fungal and Gram-negative bacterial infection GENETICS-2021-304672R1. in press.

Hanson, M.A., Cohen, L.B., Marra, A., Iatsenko, I., Wasserman, S.A. and Lemaitre, B. (2021) The Drosophila Baramicin polypeptide gene protects against fungal infection. PLoS Pathogens https://doi.org/10.1371/journal.ppat.1009846.

Lin S.J.H, Cohen L.B., Wasserman S.A. (2020) Effector specificity and function in Drosophila innate immunity: Getting AMPed and dropping Boms. PLoS Pathogens 16(5): e1008480. Full text

Cohen, L.B., Lindsay, S.A., Lin, S.J.H., Xu, Y., and Wasserman S.A. (2020) The Daisho peptides mediate Drosophila defense against a subset of filamentous fungi. Front. Immunol. doi: 10.3389/fimmu.2020.00009. Full text

Lin, S.J.H., Fulzele, A., Cohen, L.B., Bennett, E.J., and Wasserman S.A. (2020) Bombardier Enables Delivery of Short-Form Bomanins in the Drosophila Toll Response. Front. Immunol. 10.3389/fimmu.2019.03040. Full text

Lindsay, S.A., Lin, S.J.H., and Wasserman S.A. (2018) Short-Form Bomanins Mediate Humoral Immunity in Drosophila. J. Innate Immunity. 10:306-314. Full text

Zhou, B., Lindsay, S.A., and Wasserman S.A (2015). Alternative NF-κB isoforms in the Drosophila neuromuscular junction and brain. PLoS One. 10(7):e0132793. Full text

Ko, K., Root, C.M., Lindsay, S.A., Zaninovich, O.A., Shepherd, A.K., Wasserman, S.A., Ki, S.M., and Wang J.W. (2015) Starvation promotes concerted modulation of appetitive olfactory behavior via parallel neuromodulatory circuits. Elife. 4:e08298.Full text

Clemmons, A.W., Lindsay, S.A., and Wasserman S.A (2015). An effector peptide family required for Drosophila Toll-mediated immunity. PLoS Pathogens. 11(4):e1004876. Full text

Higgins, R., Gendron, J.M., Rising, L., Mak, R., Webb, K., Kaiser, S.E., Zuzow, N., Riviere, P., Yang, B., Fenech, E., Tang, X., Lindsay, S.A., Christianson, J.C., Hampton, R.Y., Wasserman, S.A., and Bennett, E.J. (2015). The unfolded protein response triggers site-specific regulatory ubiquitylation of 40S ribosomal proteins. Mol. Cell. pii: S1097-2765(15)00308-1. Full text

Lindsay, S.A., and Wasserman S.A. (2014) Conventional and non-conventional Drosophila Toll signaling. Dev. Comp. Immunol.,42, 16-24. Full text.

Daigneault, J., Klemetsaune, L., and Wasserman S.A. (2013) The IRAK homolog Pelle is the functional counterpart of IκB Kinase in the Drosophila Toll pathway. PLoS One, 8:e75150. Full text

Clemmons, A.W., and Wasserman S.A. (2013) Combinatorial effects of transposable elements on gene expression and phenotypic robustness in Drosophila melanogaster. G3: Genes, Genomes, Genetics, 3, 1531-1538.Full text.

Lattao, R., Bonaccorsi, S., Guan, X., Wasserman S.A., and Gatti, M. (2011) Tubby-tagged balancers for the Drosophila X and second chromosomes. Fly. 5, 369-370. Full text

Wasserman S.A. (2010) Structural biology: Immunity takes a heavy Toll. Nature. 465, 882-883. Full text

Towb, P., Sun, H., and Wasserman S.A. (2009) Tube is an IRAK-4 homolog in a Toll pathway adapted for development and immunity. J. Innate Immunity. 1, 309-321. Full text

Busse M.S., Arnold C.P., Towb, P., Katrivesis J., and Wasserman S.A. (2007) A κB sequence code for pathway-specific innate immune responses. EMBO J. 26, 3826-3835. Full text

Franklin-Dumont, T.M., Chatterjee, C., Wasserman, S.A., and DiNardo,S. (2007) A novel EIF4G homolog, Off-schedule, couples translational control to meiosis and differentiation in Drosophila spermatocytes. Development. 134, 2851-2861. Full text

Guan X, Middlebrooks B.W., Alexander S., and Wasserman S.A. (2006). Mutation of TweedleD, a member of an unconventional cuticle protein family, alters body shape in Drosophila.  Proc. Natl. Acad. Sci. USA. 103, 16794-16799. Full text

Wasserman, S. A. (2004). Nature's fortress against infection.  Nature Immunology 5, 474-475.  Full text

Park, J. M, Brady, H., Ruocco, M. G., Sun, H., Williams, D., Lee, S. J., Kato Jr., T., Richards, N., Chan, K., Mercurio, F., Karin, M., and Wasserman, S.A. (2004).  Targeting of TAK1 by the NF-κB protein Relish regulates the JNK-mediated immune response in Drosophila.  Genes Dev. 18, 584-594.   Full text

Sun, H., Towb, P., Chiem, D. N., Foster, B .A., and Wasserman, S.A. (2004).  Regulated assembly of the Toll signaling complex drives Drosophila dorsoventral patterning.  EMBO J. 23, 100-110.   Full text

Sun, H., Bristow, B. N., Qu, G., and Wasserman, S. A.  (2002)  A heterotrimeric death domain complex in Toll signaling.  Proc. Natl. Acad. Sci. USA 99, 12871-12876.  Full text

Towb, P., Bergmann, A., and Wasserman, S. A. (2001).  The protein kinase Pelle mediates feedback regulation in the Drosophila Toll signaling pathway.  Development 128, 4729-4736.  Full text

Afshar, K., Gonczy, P., DiNardo, S., and Wasserman, S. A. (2001).  fumble encodes a pantothenate kinase homolog required for proper mitosis and meiosis in Drosophila melanogasterGenetics 157, 1267-1276. Full text

Wasserman, S. A. (2000). Toll signaling: the enigma variations. Curr. Opin. Gen. Dev. 10, 497-502.  Full text

Afshar, K., Stuart, B., and Wasserman, S. A. (2000).  Functional analysis of the Drosophila Diaphanous FH protein in early embryonic development.  Development 127, 1887-1897. Full text

Zapata, J.M., Matsuzawa, S., Godzik, A., Wasserman, S.A., and Reed, J.C. (2000).  The Drosophila TNF-receptor associated factor-1 (DTRAF1) interacts with Pelle and regulates NF-κB activity.  J. Biol. Chem., 275, 12102-12107.  Full text

Xiao, T., Towb, P., Wasserman, S.A., and Sprang, S.R. (1999).  Three-dimensional structure of a complex between the death domains of Pelle and Tube.  Cell, 99, 545-555.  Full text

Maines, J. Z., and Wasserman, S. A. (1999). Post-transcriptional regulation of the meiotic cdc25 Twine by the Dazl ortholog Boule.  Nature Cell Biol. 1, 171-174.  Full text

Thomas, J. A., Allen, J. L. Tsen, M., Dubnicoff, T., Danao, J., Liao, X. C., Cao, Z., and Wasserman, S. A. (1999).  Impaired cytokine signaling in mice lacking the Interleukin-1 Receptor Associated Kinase.  J. Immunol. 163, 978-984.  Full text

Cheng, M. H., Maines, J. Z., and Wasserman, S. A. (1998)  Biphasic subcellular localization of the DAZL-related protein Boule in Drosophila spermatogenesis.  Devel. Biol. 204, 567-576.  Full text

Towb, P., Galindo, R. L., and Wasserman, S. A. (1998).  Recruitment of Tube and Pelle to signaling sites at the surface of the Drosophila embryo.  Development 125, 2443-2450. Full text

Wasserman, S. A. (1998).  FH proteins as cytoskeletal organizers.  Trends Cell Biol. 8, 111-115.  Full text

Houston, D. W., Zhang, J., Maines, J. Z., Wasserman, S. A., and King, M. L.  (1998)  A Xenopus DAZ-like gene encodes an RNA component of germ plasm and is a functional homologue of Drosophila bouleDevelopment 125, 171-180.  Full text

Maines, J. Z., and Wasserman, S. A. (1998). Regulation and execution of meiosis in Drosophila males.  In Current Topics in Developmental Biology, Vol. 37 (M. A. Handel, editor) Academic Press, San Diego. Full text

Liu, Z-P., Galindo, R. L., and Wasserman, S. A. (1997).  A role for CKII phosphorylation of the Cactus PEST domain in dorsoventral patterning of the Drosophila embryos.  Genes  Devel. 11, 3413-3422.  Full text

Edwards, D. N., Towb, P., and Wasserman, S. A.  (1997). An activity-dependent network of interactions links the Rel protein Dorsal with its cytoplasmic regulators.  Development 124, 3855-3864. Full text

Cenci, G., Rawson, R., Belloni, G., Castrillon, D. H., Tudor, M., Petrucci, R., Goldberg, M. L., Wasserman, S. A., and Gatti, M.  (1997). UbcD1, a Drosophila ubiquitin conjugating enzyme required for proper telomere behavior.  Genes  Devel. 11, 863-875. Full Text

Ryner, L. C., Goodwin, S. F., Castrillon, D. H., Anand, A., Villela, A., Baker, B. S., Hall, J. C., Taylor, B. J., and Wasserman, S. A. (1996).  Control of male sexual behavior and sexual orientation in Drosophila by the fruitless gene.  Cell 87, 1079-1089.  Full Text

Reach, M., Galindo, R. L., Towb, P., Allen, J. A., Karin, M., and Wasserman, S. A. (1996).  A gradient of Cactus protein degradation establishes dorsoventral polarity in the Drosophila embryo.  Devel. Biol. 180, 353-364.  Full text

Eberhart, C. G., Maines, J. Z., and Wasserman, S. A. (1996).  Meiotic cell cycle requirement for a fly homolog of human Deleted in AzoospermiaNature 381, 783-785. Full Text

Eberhart, C. G., and Wasserman, S. A. (1995).  The pelota locus encodes a protein required for meiotic cell division: an analysis of G2/M arrest in Drosophila spermatogenesis.  Development 121, 3477-3486.  Full Text

Galindo, R. L., Edwards, D. N., Gillespie, S. K. H., and Wasserman, S. A.  (1995). Interaction of the pelle kinase with the membrane-associated protein tube is required for transduction of the dorsoventral signal in Drosophila embryos.  Development 121, 2209-2218.  Full text

Gillespie, S. K. H., and Wasserman, S. A.  (1994). dorsal, a Drosophila  rel-like protein, is phosphorylated upon activation of the transmembrane protein Toll.  Mol. Cell. Biol. 14, 3559-3568.  Full text

Castrillon, D. H., and Wasserman, S. A. (1994).  diaphanous is required for cytokinesis in Drosophila and shares domains of similarity with the products of the limb deformity gene.  Development 120, 3367-3377.  Full text

Castrillon, D. H., Gönczy, P., Alexander, S., Rawson, R., Eberhart, C., Viswanathan, S., DiNardo, S., and Wasserman, S. A. (1993). Toward a molecular genetic analysis of spermatogenesis in Drosophila melanogaster: characterization of male-sterile mutants generated by single P element mutagenesis. Genetics 135, 489-505.  Full tex

Wasserman, S. A. (1993). A conserved signal transduction pathway regulating the activity of the rel-like proteins dorsal and NF-κB.  Mol. Biol. Cell 4, 767-771. Full text

Shelton, C. A., and Wasserman, S. A. (1993) pelle encodes a protein kinase required to establish dorsoventral polarity in the Drosophila embryo.  Cell 72, 515-525.  Full text

Letsou A, Alexander S, Wasserman SA. (1993) Domain mapping of tube, a protein essential for dorsoventral patterning of the Drosophila embryo. EMBO J. 12:3449-3458.  Full text

Avery L., and Wasserman, S. A. (1992) Ordering gene functions: the interpretation of epistasis in regulatory hierarchies.  Trends in Genetics 8, 312-316.  Full text

Letsou A, Alexander S, Orth K, Wasserman SA. (1991) Genetic and molecular characterization of tube, a Drosophila gene maternally required for embryonic dorsoventral polarity.  Proc Natl Acad Sci U S A. 1991 Feb 1;88:810-814. Full text