Signaling in Innate Immunity and Development

  Research in the Wasserman lab centered on the question of how information is encoded, transmitted, and interpreted in living systems. To address this question, we focused on a signal transduction pathway shared between insects and humans. Most of our studies were carried out on the fruit fly, where we could use genetic methods to disrupt pathway function, monitor and manipulate gene activity, and map out regulatory circuits using molecular, biochemical, and bioinformatic techniques.
  As an international group of graduate and undergraduate students, postdoctoral fellows, and highly skilled research associates, we collectively generated an intellectual and technical infrastructure that facilitated discovery. By design, the lab offered a supportive and challenging environment that fostered creativity, collaboration and camaraderie.
  Students and postdocs gained experience and guidance in formulating projects, writing and reviewing manuscripts, developing fellowship and grant proposals, giving research talks, mentoring trainees, and establishing careers as the next generation of leaders in biomedical research.

Recognition and Response in Innate Immunity
Mechanisms of Signal Transduction
Pattern Formation in Embryos