We are interested in how information is encoded, transmitted, and interpreted in living systems. To address this question, we focus on a pathway shared between insects and humans that has functions in development and defense. Our studies focus on the fruit fly, where we can use genetic methods to disrupt pathway function, monitor and manipulate gene activity, and map out regulatory circuits using molecular, biochemical, and bioinformatic techniques.
  As an international group of graduate and undergraduate students, postdoctoral fellows, and highly skilled research associates, we collectively generate an intellectual and technical infrastructure that facilitates discovery. The lab offers a supportive and challenging environment that fosters creativity, collaboration and camaraderie. We also have fun together and celebrate success.
  Students and postdocs gain experience and guidance in formulating projects, writing and reviewing manuscripts, developing fellowship and grant proposals, giving research talks, mentoring trainees, and establishing careers as the next generation of leaders in biomedical research.

Recognition and Response in Innate Immunity

Mechanisms of Signal Transduction

Pattern Formation in Embryos