Signaling in Innate Immunity and Development
We are interested in how information is encoded, transmitted, and interpreted in living systems. To address this question, we focus on a pathway shared between insects and humans that has functions in development and defense. Our studies focus on the fruit fly, where we can use genetic methods to disrupt pathway function, monitor and manipulate gene activity, and map out regulatory circuits using molecular, biochemical, and bioinformatic techniques. |
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Recognition and Response in Innate Immunity |
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Mechanisms of Signal Transduction |
Pattern Formation in Embryos |