Recent Publications

Gaudry Q, Kristan WB Jr. (2009) Behavioral choice by presynaptic inhibition of tactile sensory terminals. Nat Neurosci 12:1450-7.  PMID: 19801989

Kristan W.B. (2008) Neuronal decision-making circuits. Curr Biol 18:R928-32.

Briggman K.L., Kristan W.B. Jr. (2008) Multifunctional pattern generating circuits. Annu Rev Neurosci 31:271-294.

Mesce KA, Esch T, Kristan WB Jr (2008) Cellular substrates of action selection: A cluster of higher-order descending neurons shape body posture and locomotion. J Comp Physiol A 194:469-81. 118.

Fortin D.L., Banghart M.R., Dunn T.W., Borges K., Wagenaar D.A., Gaudry Q., Karakossian M.H., Otis T.S., Kristan W.B., Trauner D, Kramer R.H. (2008) Photochemical control of endogenous ion channels and cellular excitability. Nature Methods 5:331-338.

Baca S.M., Marin-Burgin A, Wagenaar D.A., Kristan W.B. Jr. (2008) Widespread inhibition proportional to excitation controls the gain of a leech behavioral circuit. Neuron, 57:276-89.

Marin-Burgin A., Kristan W.B. Jr., French K.A. (2008) From synapses to behavior: Development of a sensory-motor circuit in the leech. Special issue of Dev Neurobiology 68:779-787.

Kristan W.B., Gillette, R. (2007) Decision-making in small neuronal networks. In: Invertebrate Neurobiology, Ed. by G. North, R. Greenspan, Cold Spring Harbor Laboratory Press, New York, pp. 533-554.

Friesen W.O., Kristan W.B. Jr. (2007) Leech locomotion: Swimming, crawling, and decisions. Curr Opin Neurobiol 17:704-711.

Kristan WB (2007) A push-me pull-you neural design. Science 315:339-40.

Briggman KL, Abarbanel HDI, Kristan WB Jr (2006) From crawling to cognition: analyzing the dynamical interactions among populations of neurons. Curr Opin Neurobiol 16:135-44.

Thomson EE, Kristan WB (2006) Encoding and decoding touch location in the leech CNS. J Neurosci 26:8009-16.

Briggman KL, Kristan WB Jr (2006) Imaging dedicated and multifunctional neural circuits generating distinct behaviors. J Neurosci 26:10925-33.

Kristan WB, Katz P (2006) Form and function in systems neuroscience. Curr Biol 16:R828-31.

Cornford A, Kristan WB 3rd, Malnove S, Kristan WB Jr, French KA Functions of the subesophageal ganglion in the medicinal leech revealed by ablation of neuromeres in embryos. J Exp Biol. 2006 Feb 1;209(Pt 3):493-503.

Kristan WB Jr, Calabrese RL, Friesen WO. Neuronal control of leech behavior. Prog Neurobiol. 2005 Aug;76(5):279-327.

Marin-Burgin A, Eisenhart FJ, Kristan WB Jr, French KA. Embryonic electrical connections appear to prefigure a behavioral circuit in the leech CNS. J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2006 Feb;192(2):123-33.

French KA, Chang J, Reynolds S, Gonzalez R, Kristan WB 3rd, Kristan WB Jr. Development of swimming in the medicinal leech, the gradual acquisition of a behavior. J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2005 Sep;191(9):813-21.

Thomson EE, Kristan WB. Quantifying stimulus discriminability: a comparison of information theory and ideal observer analysis. Neural Comput. 2005 Apr;17(4):741-78.

Marin-Burgin A, Eisenhart FJ, Baca SM, Kristan WB Jr, French KA. Sequential development of electrical and chemical synaptic connections generates a specific behavioral circuit in the leech. J. Neurosci. 2005 Mar 9;25(10):2478-89

Briggman KL, Abarbanel HD, Kristan WB Jr. Optical imaging of neuronal populations during decision-making. Science. 2005 Feb 11;307(5711):896-901.

Baca SM, Thomson EE, Kristan WB Jr. Location and intensity discrimination in the leech local bend response quantified using optic flow and principal components analysis. J Neurophysiol. 2005 Jun;93(6):3560-72.

Taylor AL, Cottrell GW, Kleinfeld D, Kristan WB Jr. Imaging reveals synaptic targets of a swim-terminating neuron in the leech CNS. J Neurosci. 2003 Dec 10;23(36):11402-10

Esch T, Mesce KA, Kristan WB. Evidence for sequential decision making in the medicinal leech. J Neurosci. 2002 Dec 15;22(24):11045-54.

Taylor AL, Cottrell GW, Kristan WB Jr. Analysis of oscillations in a reciprocally inhibitory network with synaptic depression. Neural Comput. 2002 Mar;14(3):561-81.

Kristan WB Jr, Eisenhart FJ, Johnson LA, French KA. Development of neuronal circuits and behaviors in the medicinal leech. Brain Res Bull. 2000 Nov 15;53(5):561-70.

Eisenhart FJ, Cacciatore TW, Kristan WB Jr. A central pattern generator underlies crawling in the medicinal leech. J Comp Physiol [A]. 2000 Jul-Aug;186(7-8):631-43.

Johnson LA, Kristan WB, Jellies J, French KA. Disruption of peripheral target contact influences the development of identified central dendritic branches in a leech motor neuron in vivo. J Neurobiol. 2000 Jun 15;43(4):365-78.

Cacciatore TW, Rozenshteyn R, Kristan WB Jr. Kinematics and modeling of leech crawling: evidence for an oscillatory behavior produced by propagating waves of excitation. J Neurosci. 2000 Feb 15;20(4):1643-55.

Wessel R, Kristan WB Jr, Kleinfeld D. Dendritic Ca(2+)-activated K(+) conductances regulate electrical signal propagation in an invertebrate neuron. J Neurosci. 1999 Oct 1;19(19):8319-26.

Shaw BK, Kristan WB Jr. Relative roles of the S cell network and parallel interneuronal pathways in the whole-body shortening reflex of the medicinal leech. J Neurophysiol. 1999 Sep;82(3):1114-23.

Cacciatore TW, Brodfuehrer PD, Gonzalez JE, Jiang T, Adams SR, Tsien RY, Kristan WB Jr, Kleinfeld D. Identification of neural circuits by imaging coherent electrical activity with FRET-based dyes. Neuron. 1999 Jul;23(3):449-59.

Wessel R, Kristan WB Jr, Kleinfeld D. Supralinear summation of synaptic inputs by an invertebrate neuron: dendritic gain is mediated by an "inward rectifier" K(+) current. J Neurosci. 1999 Jul 15;19(14):5875-88.

Deitmer JW, Kristan WB Jr. Glial responses during evoked behaviors in the leech. Glia. 1999 Apr;26(2):186-9.