Undergraduate teaching:

 

Course code:  BIMM 194

Title:              The Gambling Cell: How Random Events Drive Development and Diseases

Instructor:      Dr. Gurol Suel

 

Description:

Have you ever wondered why a single cell in your body can turn into a cancer, while many other cells just next to it don’t, even though they are all genetically identical?  Or why not all cells respond in the same way to a given stimulus or drug?  The surprising answer turns out to involve “chance” or “randomness”.  In this course we will discuss recent scientific papers that uncovered chance events in biology.  We will explore examples that show how random events are in fact deeply rooted in the molecular interactions that underlie all biological processes. We will discuss examples ranging from the function of proteins to development of flies and microbial resistance to antibiotic.  At the end of the course you will understand how and why cells sometimes “gamble” or “flip a coin” to make a decision and what happens when these fundamental cellular processes go wrong.

 

Prerequisites:

BIMM 100 (Molecular Biology); upper-division standing

 

 

Graduate teaching:


Course code:  BGGN 214

Title:              Introduction to Quantitative Biology

Instructor:      Dr. Gurol Suel

 

Course description:

The course goal is to discuss and work through example problems where quantitative biology approaches were necessary to yield novel insights.  Problems will be presented across spatial and temporal scales and with a historic perspective to instill a philosophy for understanding the scientific method and process. We will begin with atomic interactions within proteins, then genetic networks and cellular physiology, and finally cover development and conclude with population dynamics. We will also discuss the importance of connecting principles from desperate fields. Students will also be presented with examples of paradigm shifts driven by asking questions from different perspectives and understanding when, how and why q-bio approaches can be effective.