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Sensory systems detect features of the external world, which are represented in the activity of ensembles of neurons in the brain. Our lab seeks to understand these representations and how they acquire meaning that can be used to drive behavior. We exploit the sense of smell because it is a key sensory modality for rodents and elicits both innate and experience-dependent behaviors. We employ endoscopic 2-photon calcium imaging to monitor neuronal activity, and use molecular genetics, viral tracing and optogenetics to trace and manipulate the neural circuits of the mouse brain.



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