List of Publications

This is a list of recent publications.

List of publications:


Matthew A. Kinseth, Christophe Anjard, Danny Fuller, Gianni Guizzunti, William F. Loomis, and Vivek Malhotra (2007). The Golgi associated protein GRASP is required for unconventional protein secretion during development. Cell.  In press

Guizzunti G, Brady TP, Malhotra V, Theodorakis EA. (2006).Trifunctional norrisolide probes for the study of Golgi vesiculation. Bioorg Med Chem Lett.  Nov 6. (Pubmed)

Pecot MY, Malhotra V. (2006). The Golgi apparatus maintains its organization independent of the endoplasmic reticulum. Mol Biol Cell.  12:5372-80. (Pubmed)

Bard F, Malhotra V. (2006). The formation of TGN-to-plasma-membrane transport carriers. Annu Rev Cell Dev Biol.  22:439-55. (Pubmed)

Malhotra V, Mayor S. (2006).  Cell biology: the Golgi grows up. Nature 41:939-40. (Pubmed)

Guizzunti, G., Brady, T.P., Malhotra, V., Theodorakis, E.A. (2006). Chemical analysis of norrisolide-induced Golgi vesiculation.  J Am Chem Soc. Apr 5. (Pubmed)

Bard, F., Casano, L., Mallabiabarrena, A., Wallace, E., Saito,K., Kitayama, H., Guizzunti, G., Hu, Y., Wendler, F., DasGupta, R., Perrimon, N. and Malhotra, V. (2006). Functional genomics reveals genes involved in protein secretion and Golgi organization. Nature. Feb 2

Malhotra, V. and Yaffe, M.P. (2005). Membranes and organelles: Regulating the size, shape, and plasticity of cellular compartments. Curr. Opin. Cell Biol. 17. (Pubmed)

Sütterlin, C., Polishchuk, R., Pecot, M., and Malhotra, V. (2005). The Golgi-associated Protein GRASP65 Regulates Spindle Dynamics and Is Essential for Cell Division. Mol. Biol. Cell. May 11. (Pubmed)

Díaz Añel, A.M., and Malhotra, V. (2005). PKCeta is required for b1g2/b3g2 and PKD mediated transport to the cell surface and the organization of the Golgi apparatus. J. Cell Biol. 169:83-91. (Pubmed)

Brady, T.P., Wallace, E.K., Kim, S.H., Guizzunti, G., Malhotra, V., and Theodorakis, E.A. (2004). Fragmentation of Golgi membranes by norrisolide and designed analogues. Bioorg. Med. Chem. Lett. 14: 5035-5039. (Pubmed)

Yeaman, C., Ayala, M.I., Wright, J.R., Bard, F., Bossard, C., Ang, A., Maeda, Y.,  Seufferlein, T., Mellman, I., Nelson, W.J., and Malhotra, V. (2004). Protein kinase D regulates basolateral membrane protein exit from trans-Golgi network. Nat. Cell Biol. 6: 106-112. (Pubmed) 

Pecot, M.Y., and Malhotra, V. (2004). Golgi membranes remain segregated from the Endoplasmic Reticulum during mitosis in mammalian cells. Cell 116: 99–107.(Pubmed)

Shemesh, T., Luini, A., Malhotra, V., Burger, K.N.J., and Kozlov, M.M. (2003). Prefission constriction of Golgi tubular carriers driven by local lipid metabolism: a theoretical model. Biophys. J. 85: 3813–3827. (Pubmed)

Bard, F., Mazelin, L., Pechoux-Longin, C., Malhotra, V., and Jurdic, P. (2003). Src regulates Golgi structure and KDEL receptor-dependent retrograde transport to the Endoplasmic Reticulum. J. Biol. Chem. 278: 46601-46606.

Colanzi A., Sütterlin, C., and Malhotra, V. (2003). Cell-cycle-specific Golgi fragmentation: how and why?. Curr. Opin. Cell Biol. 15:1-6.

Colanzi A., Sütterlin, C., and Malhotra, V. (2003). RAF1-activated MEK1 is found on the Golgi apparatus in late prophase and is required for Golgi complex fragmentation in mitosis. J. Cell Biol. 162: 27-32 .

Sütterlin, C., Hsu, P., Mallabiabarrena, A., and Malhotra, V. (2002). Fragmentation and Dispersal of the Pericentriolar Golgi Complex is Required for Entry into Mitosis in Mammalian Cells. Cell 109: 359-369 .

Baron, C.L., and Malhotra, V. (2002). Role of Diacylglycerol in PKD Recruitment to the TGN and Protein Transport to the Plasma Membrane. Science 295: 325-328 .

Van Lint, J., Rykx, A., Maeda, Y., Vantus, T., Sturany, S., Malhotra, V., Vandenheede, J.R., and Seufferlein, T.(2002). Protein kinase D: an intracellular traffic regulator on the move. Trends Cell Biol. 12: 193-200 .

Maeda, Y., Beznoussenko, G.V., Van Lint, J., Mironov, A.A., and Malhotra, V. (2001). Recruitment of Protein kinase D to the Trans Golgi Network via the first Cysteine Rich Domain. EMBO J. 20:5982-90 .

Sütterlin, C., Lin, C-Y., Feng, Y., Ferris, D., Erickson, R., and Malhotra, V. (2001). Polo-like kinase is required for the fragmentation of the pericentriolar Golgi stacks during mitosis. Proc. Natl. Acad. Sci. USA 98: 9128-9132 .

Jamora, C., Theodorakis, M.A., Malhotra, V., Theodorakis, E.A. (2001). Investigation of the biological mode of clerocidin using a whole cell assay. Bioorg. Med. Chem. 9:1365-70 .

Liljedahl, M., Maeda, Y., Colanzi, A., Ayala, I., Van Lint, J., and Malhotra, V. (2001). Protein Kinase D regulates the fission of cell surface destined transport carriers from the tans-Golgi network. Cell 104:409-420 .

Colanzi, A., Deerinck, T.J., Ellisman, M.H., and Malhotra, V. (2000). A specific activation of the mitogen-activated protein kinase kinase 1 (MEK1) is required for Golgi fragmentation during mitosis. J. Cell Biol. 149 :331-339.

Jamora, C., Yamanouye, N., Van Lint, J., Laudenslager, J., Vandenheede, J.R., Faulkner, D.J., and Malhotra, V. (1999). Gbetagamma-mediated regulation of Golgi organization is through the direct activation of protein kinase D. Cell 98:59-68.

Glick, B.S., and Malhotra, V. (1998). The curious status of the Golgi apparatus. Cell 95:883-889.

Warren, G., and Malhotra, V (1998). The organization of the Golgi complex. Curr. Opin. Cell Biol. 10:493-498.

Acharya, U., Mallabiabarrena, A., Acharya, J., and Malhotra, V. (1998). Signaling via mitogen-activated protein kinase kinase (MEKK) is required for Golgi fragmentation during mitosis. Cell 92:83-192.

Jamora, C., Takizawa, P., Zaarour, R. Denesvre, C., Faulkner, D., and Malhotra, V. (1997). Regulation of Golgi structure through heterotrimeric g proteins. Cell 92:183-192.

Stanley, H., Botas, J., and Malhotra, V. (1997). The mechanism of Golgi segregation during mitosis is cell type specific. Proc. Natl. Acad. Sci. USA 94:14467-14470.

Mironov, A., Colanzi, A., Fiucci, G., Flati, S., Fusella, A., Polishchuk, R., Tullio, G., Malhotra, V., Corda, D., Matteis, M., and Luini, A. (1997). Role of NAD+ and ADP-ribosylation in the maintenance of the Golgi structure. J. Cell Biol. 139:1109-1118 .

Emr, S. and Malhotra, V. (1997). Membranes and Sorting; Editorial overview. Curr. Opin. Cell Biol. 9:475-477.

Denesvre, C., and Malhotra, V. (1996). Membrane fusion in organelle biogenesis. Curr. Opin. Cell Biol. 8:519-523.

Acharya, U., and Malhotra, V. (1996). Formation of Golgi stacks from vesiculated Golgi membranes. Cold Spring. Harb. Symp. "protein Kinesis" vol. LX: 559-566.

Acharya, U., McCaffery, J.M., Jacobs, R., and Malhotra, V. (1995). Reconstitution of vesiculated Golgi membranes into stacks of cisternae: requirement of NSF in stack formation. J. Cell Biol. 129:577-589. 

Mallabiabarrena, A. and Malhotra, V. (1995). Vesicle biogenesis: the coat connection. Cell 83:667-669.

Acharya, U., Jacobs, R., Peters, J-M., Watson, N., Farquhar, M. and Malhotra, V. (1995). The formation of Golgi stacks from vesiculated Golgi membranes requires two distinct fusion events. Cell 82:895-904. 

Acharya, U., Elkins, K., Vance, J. and Malhotra, V. (1995). Keeping Golgi membranes intact in the pericentriolar region of mammalian cells. Biochem. Soc. Trans. 23:538-541.

Ripoche, J., Link, B., Yucel, J.K., Tokuyasu, K., and Malhotra, V. (1994). Location of Golgi Membranes with Reference to Dividing Nuclei in Syncytial Drosophila Embryos. Proc. Natl. Acad. Sci. USA 91: 1878-1882.

Veit, B., Yucel, J.K. and Malhotra V. (1993). Microtubule independent vesiculation of Golgi membranes and the reassembly of vesicles into Golgi stacks. J. Cell Biol. 122:1197-1206.

Takizawa, P.A., Yucel, J.K., Veit, B., Faulkner, D.J., Deerinck, T., Soto, G., Ellisman, M. and Malhotra, V. (1993). Complete vesiculation of Golgi membranes and inhibition of protein transport by a novel sea sponge metabolite, ilimaquinone. Cell 73:1079-1090.