Publications Recent Papers University of California, San Diego Department of Neurosciences Center for Molecular Genetics (CMG) Room 220 9500 Gilman Drive La Jolla, CA 92093-0634 Research People Home Alumni Directions Photos Downloads Malinow R. Mainen ZF, Hayashi Y. LTP mechanisms: from silence to four-lane traffic. Curr Opin Neurobiol. 2000 Jun;10(3):352-7. Malinow R, Malenka RC. AMPA receptor trafficking and synaptic plasticity. Annu Rev Neurosci. 2002;25:103-26. Malinow R. AMPA receptor trafficking and long-term potentiation. Philos Trans R Soc Lond B Biol Sci. 2003 Apr 29;358(1432):707-14. Boehm J, Malinow R. AMPA receptor phosphorylation during synaptic plasticity. Biochem Soc Trans. 2005 Dec;33(Pt 6):1354-6. Kopec C, Malinow R. Neuroscience. Matters of Size. Science. 2006 Dec 8;314(5805):1554-5. Recent Reviews Zaman SH, Parent A, Laskey A, Lee MK, Borchelt DR, Sisodia SS, Malinow R. Enhanced synaptic potentiation in transgenic mice expressing presinilin 1 familial Alzheimer’s disease mutation is normalized with a benzodiazepene. Neurobiol Dis. 2000 Feb;7(1);54-63. Hayashi Y, Shi SH, Esteban JA, Piccini A, Poncer JC, Malinow R. Driving AMPA receptors into synapses by LTP and CaMKII: requirement for GluR1 and PDZ domain interaction. Science. 2000 Mar 24;287(5461):2262-7. Zhu JJ, Esteban JA, Hayashi Y, Malinow R. Postnatal synaptic potentiation: delivery of GluR4-containing AMPA receptors by spontaneous activity. Nat Neurosci. 2000 Nov;3(11):1098-106. Shi S, Hayashi Y. Esteban JA, Malinow R. Subunit-specific rules governing AMPA receptor trafficking to synapses in hippocampal pyramidal neurons. Cell. 2001 May 4;105(3):331-43. Poncer JC, Malinow R. Postsynaptic conversion of silent synapses during LTP affects synaptic gain and transmission dynamics. Nat Neurosci. 2001 Oct;4(10):989-96. Piccini A, Malinow R. Transient oxygen-glucose deprivation induces rapid morphological changes in rat hippocampal dendrites. Neuropharmacology. 2001 Nov;41(6):724-9. Zhu JJ, Malinow R. Acute versus chronic NMDA receptor blockade and synaptic AMPA receptor delivery. Nat Neurosci. 2002 Jun;5(6):513-4. Poncer JC, Esteban JA, Malinow R. Multiple mechanisms for the potentiation of AMPA receptor-mediated transmission by alpha-Ca2+/calmodulin-dependent protein kinase II. J Neurosci. 2002 Jun 1;22(11):4406-11. Piccini A, Malinow R. Critical postsynaptic density 95/disc large/zonula occludens-1 interactions by glutamate receptor 1 (GluR1) and GluR2 required at different subcellular sites. J Neurosci. 2002 Jul 1;22(13):5387-92. Barria A, Malinow R. Subunit-specific NMDA receptor trafficking to synapses. Neuron. 2002 Jul 18;35(2):345-53. Zhu JJ, Qin Y, Zhao M, Van Aelst L, Malinow R. Ras and Rap control AMPA receptor trafficking during synaptic plasticity. Cell. 2002 Aug 23;110(4):443-55. Esteban JA, Shi SH, Wilson C, Nuriya M, Huganir RL, Malinow R. PKA phosphorylation of AMPA receptor subunits controls synaptic trafficking underlying plasticity. Nat Neurosci. 2003 Feb;6(2):136-43. Takahashi T, Svoboda K, Malinow R. Experience strengthening transmission by driving AMPA receptors into synapses. Science. 2003 Mar 7;299(5612):1585-8. Kamenetz F, Tomita T, Hsieh H, Seabrook G, Borchelt D, Iwatsubo T, Sisodia S, Malinow R. APP processing and synaptic function. Neuron. 2003 Mar 27;37(6):925-37. Seidenman KJ, Steinberg JP, Huganir R, Malinow R. Glutamate receptor subunit 2 Serine 880 phosphorylation modulates synaptic transmission and mediates plasticity in CA1 pyramidal cells. J Neurosci. 2003 Oct 8;23(27):9220-8. Ehrlich I, Malinow R. Postsynaptic density 95 controls AMPA receptor incorporation during long-term potentiation and experience-driven synaptic plasticity. J Neurosci. 2004 Jan 28;24(4):916-27. Rumpel S, LeDoux J, Zador A, Malinow R. Postsynaptic receptor trafficking underlying a form of associative learning. Science. 2005 Apr 1;308(5718):83-8. Barria A, Malinow R. NMDA receptor subunit composition controls synaptic plasticity by regulating binding to CAMKII. Neuron. 2005 Oct 20;48(2):289-301. Kopec CD, Li B, Wei W, Boehm J, Malinow R. Glutamate receptor exocytosis and spine enlargement during chemically induced long-term potentiation. J Neurosci. 2006 Feb 15;26(7):2000-9. Boehm J, Kang MG, Johnson RC, Esteban J, Huganir RL, Malinow R. Synaptic incorporation of AMPA receptors during LTP is controlled by a PKC phosphorylation site on GluR1. Neuron. 2006 Jul 20;51(2):213-25. Kopec CD, Kessels HW, Bush DE, Cain CK, LeDoux JE, Malinow R. A robust method to analyze rodent motion during fear conditioning. Neuropharmacology. 2007 Jan;52(1):228-33. Boehm J, Ehrlich I, Hsieh H, Malinow R. Two mutations preventing PDZ-protein interactions of GluR1 have opposite effects on synaptic plasticity. Learn Mem. 2006 Sep-Oct;13(5):562-5. Hsieh H, Boehm J, Sato C, Iwatsubo T, Tomita T, Sisodia S, Malinow R. AMPAR removal underlies A-beta-induced synaptic depression and dendritic spine loss. Neuron. 2006 Dec 7;52(5):831-43. Ehrlich I, Klein M, Rumpel S, Malinow R. PSD-95 is required for activity-driven synapse stabilization. Proc Natl Acad Sci USA. 2007 Mar 6;104(10):4176-81. Li B, Woo RS, Mei L, Malinow R. The neuregulin-1 receptor erbB4 controls glutamatergic synapse maturity and plasticity. Neuron. 2007 May 24;54(4):583-97. Hu H, Real E, Takamiya K, Kang MG, Ledoux J, Huganir RL, Malinow R. Emotion enhances learning via norepinephrine regulation of AMPA-receptor trafficking. Cell. 2007 Oct 5;131(1):160-73. Kopec CD, Real E, Kessels HW, Malinow R. GluR1 links structural and functional plasticity at excitatory synapses. J Neurosci. 2008 Feb 6;28(6):1469-78