A. Stabell, J. Hawkins, M. Li, X. Gao, M. David, W. Press and S. Sawyer

Non-Human Primate Schlafen11 Inhibits Production of Both Host and Viral Proteins
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PLOS Pathogens 12 (12);e1006066. doi:10.1371

D. Otero, N. Fares-Frederickson, M. Xiao, D. Baker and M. David

IFN-β Selectively Inhibits IL-2 Production through CREM-Mediated Chromatin Remodeling
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Journal of Immunology (2015), doi:10.4049
T. Ohkuri, A. Ghosh, A. Kosaka, J. Zhu, M. Ikeura, M. David, S. Watkins, S. Sarkar and H. Okada
STING contributes to antiglioma immunity via triggering type I IFN signals in the tumor microenvironment
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Cancer Immunol Res. 2014 Dec;2(12):1199-208. doi: 10.1158
K. Mowen and M. David
Unconventional post-translational modifications in immunological signaling
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Nat Immunol. 2014 Jun;15(6):512-20. doi: 10.1038

M. Abdel-Mohsen, R. Raposo, X. Deng, M. Li, T. Liegler, E. Sinclair, M. Salama, H. Ghanem, R. Hoh, J. Wong, M. David, D. Nixon, S. Deeks and S. Pillai

Expression profile of host restriction factors in HIV-1 elite controllers
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Retrovirology, Vol.10, 106- (2013), doi:10.1186/1742-4690-10-106
D. Otero, D. Baker and M. David
IRF7-Dependent IFN-β Production in Response to RANKL Promotes Medullary Thymic Epithelial Cell Development
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Journal of Immunology (2013), doi:10.4049
M. Li, E. Kao, X. Gao, H. Sandig, K. Limmer, M. Pavon-Eternod, T. Jones, S. Landry, T. Pan, M. Weitzman and M. David
Codon-usage-based inhibition of HIV protein synthesis by human schlafen 11
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Nature (2012), doi:10.1038
J. Gonzalez-Navajaz, J. Lee, M. David and E. Raz
Immunemodulatory Functions of type I Interferons
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Nature Reviews|Immunology, Vol. 12 (2012), 125-135
E. Chiang, V. Veckman, K.Limmer and M. David
Phospholipase Cg-2 and Intracellular Calcium Are Required for LPS-induced TLR4 Endocytosis and IRF3 Activation
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Journal of Biological Chemistry, Vol. 287, No. 6 (2012), 3704-3709
H. Moro, D. Otero, Y. Tanabe and M. David
T Cell-Intrinsic and -Extrinsic Contributions of the IFNAR/STAT1-Axis to Thymocyte Survival
PLoS ONE (2011), doi:10.1371
M. David
Interferons and MicroRNAs
Journal of Interferon & Cytokine Research, Vol. 30, (2010), 825-828
I. Pedersen, D. Otero, E. Kao, A Miletic, C. Hother, E. Ralfkiaer, R. Rickert, K. Groenbaek and M. David
Onco-miR-155 Targets SHIP1 to Promote TNFa-dependent Growth of B cell Lymphomas
EMBO Molecular Medicine, Vol. 1, (2009), 288-295
I. Pedersen and M. David
microRNAs in the immune response
Cytokine, Vol.43, (2008), 391-394
I. Pedersen, G. Cheng, S. Wieland, S. Volinia, C. Croce, F. Chisari and M. David
Interferon Modulation of cellular microRNAs as an antiviral mechanism
Nature, Vol.449, (2007), 919-922
R. Hoyt, W. Zhu, F. Cerignoli, A. Alonso, T. Mustelin and M. David
Selective Tyrosine Dephosphorylation of Interferon-Activated Nuclear STAT5 by the VHR Phosphatase
Journal of Immunology (Cutting Edge),Vol. 179, (2007), 3402-3406
D. Otero, V. Poli, M. David and R.C. Rickert
Inherent and Acquired Resistance to Radiation-Induced Apoptosis in B Cells: A Pivotal Role for STAT3
Journal of Immunology (Cutting Edge),Vol. 177, (2006), 6593-6597
E. Chiang, O. Dang, K. Anderson, A. Matsuzawa, H. Ichijo and M. David
ASK1 is Required for ROS-Mediated Activation of IRF3 by LPS
Journal of Immunology (Cutting Edge),Vol. 176, (2006), 5720-5724
S. Ogawa, J. Lozach, C. Benner, G. Pascual, R. Tangirala, S. Westin, A. Hoffman, S. Subramaniam, M. David, M. Rosenfeld and C. Glass
Molecular Determinants of Crosstalk between Nuclear Receptors and Toll-like Receptors
Cell, Vol. 122, September 9 (2005), 707-721
S. Li, M. Wilkinson, X. Xia, M. David, L. Xu, A. Purkel-Sutton and A. Bhardwaj
Induction of IFN-regulated factors and antitumoral surveillance by transfected placebo plasmid DNA
Molecular Therapy ,Vol. 11, No. 1 (2005), 112-119
Y. Tanabe, T. Nishibori, L. Su, R.M. Arduini, D.P. Baker and M. David
Role of STAT1, STAT3 and STAT5 in IFNa/b Responses in T-Lymphocytes
Journal of Immunology (Cutting Edge),Vol. 174, (2005), 609-613
K.A. Mowen, B.T. Schurter, J.W. Fathman, M. David and L.H. Glimcher
Arginine Methylation of NIP45 Modulates Cytokine Gene Expression in Effector T Lymphocytes
Molecular Cell , Vol. 15, No. 4 (2004), 559-571
H.Y. Cheng, P.Li, M. David, T.E. Smithgall, L. Feng and M.W. Lieberman
Arsenic Inhibition of the JAK-STAT pathway
Oncogene, Vol. 23, No. 20 (2004), 3603-3612
W.A. Smith, B.T. Schurter, F. Wong-Staal and M. David
Arginine Methylation of RNA Helicase A Determines Its Subcellular Localization
Journal of Biological Chemistry, Vol. 279, No. 22 (2004), 22795-22798
O. Dang, L. Navarro and M. David
Inhibition of LPS-induced IFN-Regulatory Factor 3 Activation and Protection from Septic Shock by Hydroxystilbenes
Shock,Vol. 21, No. 5 (2004), 470-475
O. Dang, L. Navarro, K. Anderson and M. David
Anthrax Lethal Toxin Inhibits Activation of IFN-Regulatory Factor 3 by Lipopolysaccharide
Journal of Immunology (Cutting Edge),Vol. 172, (2004), 747-751
T. Nishibori, Y. Tanabe, L. Su and M. David
Impaired development of CD4+CD25+ regulatory T cells in the absence of STAT1: increased susceptibility to autoimmune disease
Journal of Experimental Medicine, Vol. 199, No. 1 (2004), 25-34
V. Ruvolo , L. Navarro, C.E. Sample, M. David, S. Sung and S. Swaminathan
The Epstein-Barr Virus SM Protein Induces STAT1 and Interferon-stimulated Gene Expression
Journal of Virology, Vol. 77, No. 6 (2003), 3690-3701
W. Zhu, T. Mustelin and M. David
Arginine Methylation of STAT1 Regulates Its Dephosphorylation by T cell Protein Tyrosine Phosphatase
Journal of Biological Chemistry, Vol. 277, No. 39 (2002), 35787-35790
J. ten Hoeve, M. Ibarra-Sanchez, Y. Fu, W. Zhu, M. Tremblay, M. David and K. Shuai
Identification of a Nuclear Stat1 Protein Tyrosine Phosphatase
Molecular and Cellular Biology, Vol. 22, No. 16 (2002), 5662-5668
M. David
Signal Transduction by Type I Interferons
BioTechniques, Vol 33, No. 4 (2002), S58-S65
K.Mowen and M. David
Analysis of Protein Arginine Methylation
Science STKE (2001)
W.A. Blesofsky, K. Mowen, R.M. Arduini, D.P. Baker, M.A. Murphy, D.L. Bowtell and M. David
Regulation of STAT Protein Synthesis by c-Cbl
Oncogene, Vol. 20, No. 50 (2001), 7326-33
K. Mowen, J. Tang, W. Zhu, B.T. Schurter, K. Shuai, H.R. Herschman and M. David
Arginine Methylation of STAT1 Modulates IFNa/b Induced Transcription
Cell, Vol. 104, March 9 (2001), 731-741
T.Deb, L. Su, L. Wong, E. Bonvini, A. Wells, M. David and G. Johnson
EGF Receptor Kinase-independent Signaling by EGF
Journal of Biological Chemistry, Vol. 276, No. 18 (2001), 15554-15560
K.Mowen and M. David
Regulation of STAT1 Nuclear Export by Jak1
Molecular and Cellular Biology, Vol. 20, No. 19 (2000), 7273-7281
L. Su and M. David
Distinct mechanisms of STAT phosphorylation via the IFNa/b Receptor: Selective Inhibition of STAT3 and STAT5 by Piceatannol
Journal of Biological Chemistry, Vol. 275, No. 17 (2000), 12661-12666
L. Navarro and M. David
p38-dependent Activation of Interferon Regulatory Factor 3 by Lipopolysaccharide
Journal of Biological Chemistry, Vol. 274, No. 50 (1999), 35535-35538
L. Su, R. Rickert and M. David
Rapid STAT phosphorylation via the B cell receptor: Modulatory Role of CD19
Journal of Biological Chemistry,Vol. 274, No. 45 (1999), 31770-31774
L. Su and M. David
Inhibition of B cell Receptor Mediated Apoptosis by IFN
Journal of Immunology, Vol.162, No.11 (1999), 6317-21
K. Mowen and M. David
Role of STAT1-SH2 Domain and STAT2 in the Nuclear Translocation of STAT1
Journal of Biological Chemistry,Vol.273, No.46 (1998), 30073-76
L. Navarro, K. Mowen, S. Rodems, B. Weaver, N. Reich, D. Spector and M. David
Cytomegalovirus Activates Interferon Immediate Early Response Gene Expression and an IRF3 Containing ISRE-binding Complex
Molecular and Cellular Biology, Vol. 18, No. 7 (1998), 3796-3802
M. Sakatsume, L. Stancato, M. David, O. Silvennoinen, J. Pierce, A. Larner and D. Finbloom
IFNg Activation of Raf-1 Is Jak1-dependent and p21-ras independent
Journal of Biological Chemistry, Vol.273, No.5 (1998), 3021-26
L. Stancato, M. Sakatsume, M. David, P. Dent, F. Dong, E. Petricoin, J. Krolewski, O. Silvennoinen, P. Saharinen, J. Pierce et al.
Beta Interferon and Oncostatin M Activate Raf-1 and Mitogen Activated Protein Kinase through a JAK1 dependent Pathway
Molecular and Cellular Biology, Vol. 17, No.7 (1997), 3833-40
M. David, Gaochao Zhou, R. Pine, J. Dixon and A. Larner
The SH2-Domain Containing Tyrosine Phosphatase PTP1D is Required for IFNa/b - induced Gene Expression
Journal of Biological Chemistry, Vol. 271, No. 27 (1996), 15862-65
M. David, E. Petricoin and A. Larner
Activation of Protein Kinase A Inhibits IFN Induction of the Jak/Stat Pathway in U266 Cells
Journal of Biological Chemistry , Vol. 271, No. 9 (1996), 4585-88
E. Petricoin, M. David, K. Igarashi, C. Benjamin, L. Ling, S. Goelz, D.S. Finbloom and A.C. Larner
Inhibition of Alpha Interferon but not Gamma Interferon Signal Transduction by Phorbol Esters is Mediated by a Tyrosine Phosphatase
Molecular and Cellular Biology, Vol.16, No.4 (1996), 1419-24
L. Stancato, M. David, C. Carter-Su, A. Larner and W. Pratt
Preassociation of STAT1 with STAT2 and STAT3 in Seperate Signalling Complexes Prior to Cytokine Stimulation
Journal of Biological Chemistry, Vol.271, No. 8 (1996), 4134-37
M. David, H. Chen, S. Goelz, A. Larner and B. Neel
Differential Regulation of the Interferon-a/b Stimulated JAK/STAT Pathway by the SH2-Domain Containing Tyrosine Phosphatase SHPTP1
Molecular and Cellular Biology, Vol.15, No.12 (1995), 7050-58
M. David, E. Petricoin, C. Benjamin, R. Pine, M. Weber and A. Larner
Requirement for MAP Kinase (ERK2) Activity in Interferon a/b-Stimulated Gene Expression Through STAT Proteins
Science Vol.269 (1995), p 1721
M. David
Transcription Factors in Interferon Signaling
Pharmacology and Therapeutics Vol. 65, No. 2 (1995), 149-61
M. David, E.F. Petricoin, K. Igarashi, G.M. Feldman, D.S. Finbloom and A.C. Larner
Prolactin activates the interferon-regulated p91 transcription factor and the Jak2 kinase by tyrosine phosphorylation
Proc. Natl. Acad. Sci. USA Vol. 91 (1994), 7174-78
D.S. Finbloom, E.F. Petricoin, R.H. Hackett, M. David, G.M. Feldman, K. Igarashi, M. Weber, M. Thorner, C.M. Silva and A.C. Larner
Growth Hormone and Erythropoietin Differentially Activate DNA-Binding Proteins by Tyrosine Phosphorylation
Molecular and Cellular Biology, Vol. 14, No. 3 (1994), 2113-18
E.F. Petricoin, M. David, P. Grimley, A.C. Larner and S. VandePol
Human Cancer Cell Lines Express A Negative Transcriptional Regulator of The Interferon Regulatory Factor Family of DNA-Binding Proteins
Molecular and Cellular Biology, Vol. 14, No. 2 (1994), 1477-86
G.M. Feldman, M.David, E.F. Petricoin III, A.C. Larner and D.S. Finbloom
Cytokines which Associate with the Signal Transducer gp130 Activate the IFN Induced p91 Transcription Factor by Tyrosine Phosphorylation
Journal of Biological Chemistry, Vol. 269, No. 14 (1994), 10747-52
M. David, P. Grimley, D.S. Finbloom and A.C. Larner
A Nuclear Tyrosine Phosphatase Downregulates Interferon Induced Gene Expression
Molecular and Cellular Biology, Vol.13, No.12 (1993), 7515-21
A.C. Larner, M. David, G.M. Feldman, K. Igarashi, R.H. Hackett, D.S. Webb, S.J. McLaughlin, E.F. Petricoin and D.S. Finbloom
Tyrosine Phosphorylation of DNA-Binding Proteins by Multiple Cytokines
Science Vol.261 (1993), p 1730-33
K. Igarashi, M. David, A.C. Larner and D.S. Finbloom
In Vitro Activation of a Transcription Factor by IFNg Requires a Membrane associated Tyrosine Kinase and is Mimicked by Vanadate
Molecular and Cellular Biology, Vol.13, No.7 (1993), 3984-89
K. Igarashi, M. David, D.S. Finbloom and A.C. Larner
In Vitro Activation of The Transcription Factor GAF by IFN Gamma: Evidence For A Tyrosine Phosphatase/Kinase Signaling Cascade
Molecular and Cellular Biology, Vol.13, No.3 (1993), 1634-40
M. David, G. Romero, J. Dixon and A.C. Larner
In Vitro Activation of the Transcription Factor ISGF3 by IFNa Involves a Membrane Associated Tyrosine Phosphatase and Tyrosine Kinase
Journal of Biological Chemistry, Vol.268, No.9 (1993), 6593-99
M. David and A.C. Larner
Activation of Transcription Factors by Interferon-alpha in a Cell-Free System
Science Vol.257 (1992), p 813